Why Shire PLC Has Beaten AstraZeneca plc And GlaxoSmithKline plc In 2014

Never mind AstraZeneca plc (LON: AZN) and GlaxoSmithKline plc (LON: GSK), Shire PLC (LON:SHP) is this year’s big pharmaceuticals winner!

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

When investing, your capital is at risk. The value of your investments can go down as well as up and you may get back less than you put in.

Read More

The content of this article is provided for information purposes only and is not intended to be, nor does it constitute, any form of personal advice. Investments in a currency other than sterling are exposed to currency exchange risk. Currency exchange rates are constantly changing, which may affect the value of the investment in sterling terms. You could lose money in sterling even if the stock price rises in the currency of origin. Stocks listed on overseas exchanges may be subject to additional dealing and exchange rate charges, and may have other tax implications, and may not provide the same, or any, regulatory protection as in the UK.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

If you invest in pharmaceuticals, Shire (LSE: SHP) is the one you should have bought this year.

It’s up 60% in the past 12 months to 4,395p, easily beating the FTSE 100‘s big two — AstraZeneca (LSE: AZN) (NYSE: AZN.US) is up a still-nice 32% to 4,618p, but GlaxoSmithKline (LSE: GSK) (NYSE: GSK.US) shares have lost 11% to 1,378p.

Rising profits

Looking at Shire’s past results, it’s not surprising the shares have done well. For the year ended December 2013, Shire reported a 77% rise in earnings per share (EPS) from continuing operations, and an underlying non-GAAP rise of 23%. That came from a 9% rise in revenue to $4.9bn, with sales of a number of key treatments for ADHD, ulcerative colitis and a wide variety of other ailments growing nicely.

The firm also has an impressive number of candidates in late stages of its development pipeline, and that’s helped inspire analysts to forecast a further 35% rise in EPS for 2014. So far this year things are looking good, with total revenues at Q3 time up 32% over the same period last year.

It’s not really surprising, then, that there’s a pretty heavy Buy consensus amongst analysts at the moment.

A revolution

Over at AstraZeneca, that 32% rise is a result that few of us would have expected so soon when new CEO Pascal Soriot took over in October 2012. At the time, the company was struggling with the loss of patent protection on a number of key drugs and the resulting competition from generic alternatives, and its development pipeline was looking unimpressive.

AstraZeneca is not back to rising EPS yet, and there’s a fall of 18% expected this year. But the about-turn that Mr Soriot has effected in such a short time has been dramatic. Non-key assets have been offloaded, AstraZeneca’s pipeline is looking dramatically better now, and we might even see EPS growth next year — about two years ahead of earlier expectations.

The recovery has put the shares on a forward P/E of 18 based on the current 2015 consensus, but coupled with a decently-covered 3.7% dividend yield and the potential value of the firm’s late-stage pipeline candidates, that could prove to be good value.

Things are looking a bit tougher at GlaxoSmithKline, and the failure to sell off a portfolio of its older drugs earlier this month didn’t impress investors — the price has dipped since it was announced.

Cheaper valuation

At the nine-month stage, revenues were down 14%. But that was in line with expectations, and there’s an end to falling EPS already forecast for 2015 (while for AstraZeneca it’s still just a hope). Dividends should yield around 5.5%, although they won’t be as well covered, and the shares are on a fairly modest P/E of just over 15.

On the whole, all three of these look like good prospects — but 2015 could easily end up belonging to Shire again.

Should you invest, the value of your investment may rise or fall and your capital is at risk. Before investing, your individual circumstances should be assessed. Consider taking independent financial advice.

Alan Oscroft has no position in any shares mentioned. The Motley Fool UK has recommended GlaxoSmithKline. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Young Caucasian woman at the street withdrawing money at the ATM
Investing Articles

Here’s how I’d target a £2k annual second income from a £20k Stocks & Shares ISA

Our writer explains how he’d try to earn thousands of pounds annually in dividends by investing a £20k ISA in…

Read more »

Mother and Daughter Blowing Bubbles
Investing Articles

5 stocks that Fools have been buying!

Our Foolish freelancers are putting their money where their mouths are and buying these stocks in recent weeks.

Read more »

Investing Articles

The £20k Stocks and Shares ISA might be one of the better things about living in the UK

The £20k Stocks and Shares ISA doesn't have many equivalents in other countries. Here's why these accounts can help UK…

Read more »

Google office headquarters
Investing Articles

Growth or income: what should my SIPP target?

Should our writer concentrate his SIPP on growth or income shares, or buy a mixture of both? Here he considers…

Read more »

Black father and two young daughters dancing at home
Investing Articles

£17,365 in savings? Here’s how I’d invest that in dividend shares for long-term passive income

Interest rates might be higher than inflation, but Stephen Wright thinks the stock market is still the place to be…

Read more »

Investing Articles

Up 1,630% in 10 years and with a 4.2% yield, here’s my favourite passive income investment

Oliver thinks Games Workshop is an exceptional company offering generous dividends for passive income. But it can't grow forever!

Read more »

Smiling white woman holding iPhone with Airpods in ear
Investing Articles

Here’s how I’d start investing with one pound a day!

Our writer explains how he’d start investing if he had his time again -- by putting aside as little as…

Read more »

British flag, Big Ben, Houses of Parliament and British flag composition
Small-Cap Shares

This 35p UK stock could rise 129%, according to a City broker

This 35p UK stock’s risky. But if analysts at Deutsche Bank are right, it could more than double investors’ money…

Read more »